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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2195258a3fbf6c4460d84855691b1b17eca712de4a26226b87ff62aa47555f' 
  AND token = '4ijzaqhlEwXZN8Noy11NY5P4wfs8TmXyS1pkCFaHEh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}