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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aa45030bd622eba2b207dd2c2e4422ebcaff1bb56f0b136a0c835505cc3216c' 
  AND token = '1bCqQtQ1AXS7nRKGjqt/otgfyh2prk65lfqkvFR72eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}