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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6c7c8639e2142c15c4eec6c0a9f9195bd783e1e0617eced4265edd524f0944' 
  AND token = 'JdZ8QuR2y0bw58Oh7mgVvJqQK8VhK9mypWVfDSv9wQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}