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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b405e1d64d8a1155d907c89212ff6e27b783bbdf1c6932b2e3b61177c8281637' 
  AND token = 'Cfh0r3PVG7CuP0AqggYZSKCJf0kikYJJCoJkoOi0TyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}