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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afa8d00adfb539ff5c832e4b40e0d2274cd751150a0fbee6a3d07ea5249d384' 
  AND token = 'Mr071HIQQhqeyh4++dbH4A1dbTv2VpFpEnhDZU3RJb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}