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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2268dd443b5cbe9c0c0624690c15ab646447da07a6c624e7a5369bf3b08949a7' 
  AND token = 'BV4g3Yv+mtHocG0IBGVdvmYJgNxOTzED6BTd9XASucw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}