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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28eb22b73bf41744614f46d150e01f4b9a12cd63c336b6bbe25a7138482362c6' 
  AND token = 'xRIrjm/ggTW5UWAeeWrcCfFMz42vU4LeaehUvxLS59I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}