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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486c21646ca0aa82fb5afe3849aa2b70da21e0e3455bfd44ee13912a5bd424fa' 
  AND token = 'JnSrVxgO+X5YUrkE2ngumS8sYhQbkG83cIeGCiOMwi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}