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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cc31a2ea35e28fe28f2a9a9f2e8eb3346246c990f53bf780fec9af7ef914e1' 
  AND token = '9yVTjsAAL3ijON4MznY66P1yM+d2u9j0/REP2WliS3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}