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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5642b39c670accfced743edc1093bf603579472337d89bac012d8b5ca4df84' 
  AND token = 'R8UIyUA35Y/e3yybyTZwQeKH32s2AcjQxxblywJdujw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}