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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a23e6083aa0fe53bfba2ac3747df12569be056c779174d5b0621e810ce4f44' 
  AND token = 'MazO8BJpdYAMI2WfJU6s9lWUmf/RdL8YHCFKyu7pYS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}