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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e865224f207e969122a84175ce59a91e8adf41fba67b18ae1b8b1b9f36e2c29e' 
  AND token = 't9++IEvqFyRbw99mPWvi1LXuP6tfiDtdS9r+fHlm8mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}