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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae907a4c43087988b1aac5150f7e3aa2a093a95083ccfa92b930a137d9e7f67' 
  AND token = 'I8xT1PPrzCJK3xDKntPP4UqmVL7K2nMaUry/d7SoyV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}