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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77dfee40f25b43e443d32410df6605f99ac1acb3ba7338bd3698673e2ea3b247' 
  AND token = '7bK3OfJb7rBGr176HOTMp4zbDP1x0hwqjjLOidNwW80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}