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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f12077ca968ba48cfff6c94699e1c38e69136927baf67d6499b54f322d7bab' 
  AND token = 'edxlXt2wl3d82q3ki/x9K4Mae3100YDEiDDjsYcmb00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}