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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4eb7e0ffb79b41366838e53f87da53e55a4a81c1b8462cae9d7f25967c40cdf' 
  AND token = 'uD4uc7jEQf71ZZZwe9GniI+z2U65DxDK/F6C9ATI5kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}