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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a86e55afc2308db68dba8f02f60f0d6da87516ca05953e47114887fdd33c410' 
  AND token = '/ktxBJMHYzTmg7FGbSc7yDykFkyh7LVs9kKn9Ir0kPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}