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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f67258b2dc75d986440b5c32c0308acabaec437795289d05222a5b010ad1e4' 
  AND token = 's3eYdhmdU/QNzrautqBJbBp1kNmCMBgXDBhhzvYb5Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}