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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429e779e11f6956f6883a860cceb7993bd7de8b888851d87780cca3a5ffd6685' 
  AND token = 'CNYu+1p1m+Tbz9yd/jBdJUBL7eS0flOvXvsecVLbFCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}