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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1132de64d6e1c91b80d43de2bc520168720d7fe9ff405e31bcf9552c29ee5417' 
  AND token = '6wRXYSKWZmos+o6toRVsgMGhQ3dA1KyNlIUCN1+YXEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}