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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc369e4726171e2534ee5e89a3bbbede110921d22e05ce15b33bbce1c7e864d' 
  AND token = 'xeCsFnFrcbM4A/sJIYhODzNNXdB3NKamuz6LB0Fe4N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}