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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824ba438fc3922be7ddde6429c0fffb3d1a02a5d7ab9d3a2ca99fead78dcf7a0' 
  AND token = 'Hkp8szDNnah/A+itW41UjHLADy0DK9pVpd87b7RYS8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}