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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08365e220ef9c1d368c3784a4f48cfb8764ef00d5d695cee7ab1db84d0498c8b' 
  AND token = 'aD/AwgLgUiaEF5gKvv2LvpW06e8ApRC4BGGb3s22cOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}