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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01553691bbd59c761c190e40d0c1487b0d5fe54bf503ccaff4736d6d223c6a81' 
  AND token = 'Va+qz8b4D0PkM0SuvhAtoNc6d5mTr7L+44IhbS/zXz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}