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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0728553f0396c3301f4e397c89d6d81a44294b35894004d4ef0dd75a49ea0c' 
  AND token = 'cFbdiIiKEFB98uCiBiHD41mYrbAmVNbFf4enYygQjUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}