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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4303db56e1f08824eaa0c23ddca03ac0b16787fc1b5ca46def5e1cb791739a0' 
  AND token = 'CKlDalsX79MG6v/3kGB3zfIcssBEhE3v66rskvqlqTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}