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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2399b9cc230944411127e5e2bc5eb3500a25bde204639d31593e98feaa407d' 
  AND token = 'O0GbqfX583tuQTGZc95oE1BMh9oxl2mD/DbvmAGuLZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}