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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfc5a29de681f752ef11aa09b6465a2a9c5303fabc4d733a46c88ad5acda8d9' 
  AND token = 'JUIbsKpi1rOnogXZTxdGnA9RF1bubSVV7HaSVy0D4z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}