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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f6f718ce14289594e75150d614fa67658409b156b9337c48c91028effff175' 
  AND token = '7MF2+j+FvEK3PYyhYPcY5muYoL0zROJcn45V6YB30lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}