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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed2d81c77cac2abc77bd7eaa3b08d2f28276848fdf9d6720a1ef39dc2648520' 
  AND token = 'YLSQ27Nn4/tz4fNqteQ072jy8whv1vGoy3zhH0zYygc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}