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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12807b384126f0a2f9f9a4ebed707c4620a8d08f2f991646ca62102ad7894a59' 
  AND token = 'ZmkfQ8AQbB/Wm7GCzX03FcfgRScZde9yeS9w3wV/8cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}