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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ecd1d4f5519ae0e09472241fdac07a2dd1615fea04d3e61c4b4e111b858a68' 
  AND token = 'FBDWzTNva8EsP25JU3fjfC643KICz330LKVUu9Jtxwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}