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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4b350fcd95d7e899d9435f86e20755df7716b933ad92245b572fb4d2c62ede' 
  AND token = 'c1d/EC5yTkfUliJypU9IpN6KOY45eQ6JomuVsP8O3Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}