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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a43d5459032524b50e094d720dfa1da75b1dbb614c87840acd7d6e61183ccaa' 
  AND token = 'ZVYhpkKOkLmp3SPHlS9xUQ71j5zs2zD1I+ZeiOcF2Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}