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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9e8db4a64bba7a6af2a6666d390b856692de8c47c0c06abc2a5a6469d67e05' 
  AND token = '1cWAD4YiuwApV1DDhERRQ8nYZSyDYvFPu2yAkS4PCrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}