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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65863bb72baa56f334d2045c8b9ee8e15a2606b59ef2e6b6224e641131d35308' 
  AND token = 'T6JaKZLSl1aopWpwzPhPAzA9ZxfG4jaf3SOspsrVDXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}