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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d86a424e72193a4491b0465f496430dada2d4d2a6d6162e74870b13846db99f' 
  AND token = 'sMQtXNmEm32Sa0cg2sNrptvvOgwFDJo7vzoIJlhIIgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}