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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1707f187a2e06a6925c410d304e97b5c25c9aab5d33e811aa2542475c708a5' 
  AND token = 'exTo1QMGV6dLOWOLV30y/xTsuGBgHrKxt3H4hOOEXcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}