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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f21da54450aabdd5caf1fb779435c2172aa81526bd32bdd05a75110132cb473' 
  AND token = 'ga15bEWnTeuvPN9bo69mcFRuGIijtlnM35WQco7LUeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}