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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23825b6780969582121ff8d1bca6eb7ec9b922f944bfa3317506e41f5e1f521f' 
  AND token = 'lFK1HdfqIZJ1Kv/3XiNn0h023QU/otTpIjkIkBCZyoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}