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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc78c4ba0b7d81e36d4dde5bbe7cb1fe7387adb7cb17d19ddff84635e71a40e' 
  AND token = 'jrkZ2ok1leUIxQTomRt5uEKjzQ0d2rZdHJp+8JRrRx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}