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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53530d532ba975a6b8611978cdd70a256087530badba1b1317c1175827f1c55d' 
  AND token = '6QDYbh++H4xTCqHWEIVHqQi0crayw2r4qEZc2SHw8lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}