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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2d6730a87367010c09e4518819812e00dcaee041222dd46ad6f99bdcff09f9' 
  AND token = '668fvX7ZTrPSrYnj3e8DOQNtXwEd0XN4UhDHQ8PpyC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}