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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f227737eb06ee27f08ab5018d741a11febf3f2d77ccae063c54591222b99e90f' 
  AND token = 'BMYiENC2R1K1X8iqNAiqBU+YG6uvVRM38aCd3IW9/90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}