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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df58c137aa11d673dfa054007610b3e994d3e6433e5970afcf6d6686c3ba68e2' 
  AND token = 'Eiv+sFDHTmn52wBsJzffydqG+nUV+6a1HqpcpXPt/x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}