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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6089ea778ba4fd5c0aec0c2a3f7316883f584e894fd55b3ee7f0dcef325c5ccc' 
  AND token = 'kJ6elxlyQTQ5Y5EgKZDsjL2iysaN7uXLdHAZKjReGE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}