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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12bcf1b717e5f3906b321cad12ac999882ff2ee4e4b2fe4a6eb91e349f8a1822' 
  AND token = 'd1rRFxRsahTdFaIdVZgIJilRNFxgFjrHmuGZaobmXpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}