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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c94ca85c619f5c2cc0897b5e73cbb32df30ad53412cab2acac6245328357926' 
  AND token = 'Z+05zsFs9/f64xW4bX7srebYtaK//lvO24oB52T68fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}