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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db72d34b6fb64f9bc337cf05322f08fbb741a6e01dfb8cb17f4952863381f51b' 
  AND token = 'CzyixwZPJWJ+lInihdI1nd1xIVW3rNIbCI5dOzWO6iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}