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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efacd9f8c897fe365c7f5b4e776bfa955cde87f86c41d3ee7a614fcdbc5930ab' 
  AND token = 'i+JDs27JRBv/xHmOZ6bCkaLls6qB8lhUWyt2+ZFcWFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}